WebSplicing factor. A splicing factor is a protein involved in the removal of introns from strings of messenger RNA, so that the exons can bind together; the process takes place in … WebApr 10, 2024 · Splicing factor SRSF3 is an oncogene and overexpressed in various kinds of cancers, however, the function and mechanism involved in colorectal cancer (CRC) remained unclear. The aim of this study was to explore the relationship between SRSF3 and carcinogenesis and progression of CRC. The expression of SRSF3 in CRC tissues was …
Splicing factors in the heart: Uncovering shared and unique targets
WebMar 21, 2024 · SRSF3 (Serine And Arginine Rich Splicing Factor 3) is a Protein Coding gene. Diseases associated with SRSF3 include Ocular Hypertension and Spinal Muscular … WebMay 30, 2013 · SRSF3 (SRp20) is a member of a highly conserved family of splicing factors that have critical roles in key biol … Most human pre-mRNA transcripts are alternatively spliced, but the significance and fine-tuning of alternative splicing in different biological processes is only starting to be understood. hand carved wooden earrings
JCI - Degradation of splicing factor SRSF3 contributes to …
WebSep 3, 2024 · The SR protein family member, SRSF3, is reportedly upregulated during oxidative stress and hypoxia, conditions typically found within a tumor, where the trans-RNA splicing factor can exert wide influence in genes associated with cell cycle and proliferation . In this study, our laboratory demonstrated an increased occurrence of both SRSF3 and ... WebMar 26, 2024 · Splicing factors TDP43 and SRSF3, which are likely responsible for the unique alternative splicing, could serve as potential targets for TNBC therapy. Abstract. Aberrant alternative splicing has been highlighted as a potential hallmark of cancer. Here, we identify TDP43 (TAR DNA-binding protein 43) as an important splicing regulator … WebMay 13, 2024 · To assess the protein expression of splicing factors, Listerman et al. and Xiao et al. additionally performed Western blots ... SRSF3 or SRSF10: We compiled 25 articles (sorted by author name) that described a minigene splicing assay on the basis of the pDESTsplice or pSpliceExpress vector systems. The physiological role of splicing variants … hand carved wooden dresser drawer pulls