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Phosphopantetheine-binding protein

WebOct 23, 2013 · The results suggest that some type I domains covalently incorporated in multidomain contexts possess potential protein binding sites missing in the equivalent regions of their respective structural templates. ... This 1136 residue long sequence is atypical since it does not possess a recognizable phosphopantetheine binding domain … WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier …

Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine …

WebJul 1, 2003 · Phosphopantetheine adenylyltransferase (PPAT) regulates the key penultimate step in the essential coenzyme A (CoA) biosynthetic pathway. PPAT catalyzes the reversible transfer of an adenylyl group from Mg2+:ATP to 4′-phosphopantetheine to form 3′-dephospho-CoA (dPCoA) and pyrophosphate. WebThe mitochondrial acyl carrier protein (human ACPM, yeast Acp1) is an essential mitochondrial protein. Through binding of nascent acyl chains on the serine (S112)-bound … sic code for energy company https://gonzojedi.com

4′‐Phosphopantetheine corrects CoA, iron, and dopamine …

WebAlthough holo-acyl carrier protein synthase, AcpS, a phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until the publication of the landmark paper by Lambalot et al.in 1996 that PPTases garnered wide-spread attention being classified as a distinct enzyme superfamily. WebJun 3, 2010 · Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine. ... Find proteins for P9WPA5 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WPA5 . Go to UniProtKB: P9WPA5. Entity Groups Sequence Clusters: WebProtein Phosphopantetheine-binding Status UniProtKB unreviewed (TrEMBL) Organism Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908) Amino acids 92 Protein existence Predicted Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add Add a publication Entry … sic code for family investment company

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Category:4′-Phosphopantetheine and Coenzyme A Biosynthesis in Plants*

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Phosphopantetheine-binding protein

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WebNov 4, 2024 · tyrosine-protein kinase is fine as a protein name but capsular polysaccharide biosynthesis would be more appropriate as a function. RimM protein, required for 16S … WebProteomics of Streptococcus mutans to Reveal the Antibiofilm Formation Mechanism of Ag/ZnO Nanocomposites with Light-Emitting Diode Radiation

Phosphopantetheine-binding protein

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WebMar 8, 2024 · A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and … WebThe OUROBOROS and SAMSARA proteins heterodimerise in a similar manner to TALE HD TF life cycle regulators in the green lineage. These observations demonstrate that TALE-HD-TF-based life cycle regulation systems have an extremely ancient origin, and that these systems have been independently recruited to regulate sporophyte developmental ...

Webprotein Summary Phosphopantetheine-binding protein (Streptomyces rimosus subsp. rimosus ATCC 10970) Cite Download Contents 1 Sequence 2 Interactions and Pathways 3 … WebJan 8, 2024 · 4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function 4'-Phosphopantetheine and long acyl …

WebThe mitochondrial acyl carrier protein (human ACPM, yeast Acp1) is an essential mitochondrial protein. Through binding of nascent acyl chains on the serine (S112)-bound 4′-phosphopantetheine (4′-PP) cofactor, ACPM is involved in mitochondrial fatty acid synthesis and lipoic acid biogenesis. Recently, yeast A Molecular Pharmacology WebNov 13, 2013 · 4ihh: Chasing acyl carrier protein through a catalytic cycle of lipid A production.

WebPhosphopantetheine-binding protein Imported. Gene names. ORF names. C4F17_18890 Imported. Organism names. Organism. Variovorax sp. PMC12 Imported. Taxonomic identifier. 2126319 NCBI. Taxonomic lineage. Bacteria > Proteobacteria > Betaproteobacteria > Burkholderiales > Comamonadaceae > Variovorax. ... Similar …

WebPhosphopantetheine-binding site.: (A) Structural superposition of ATP-bound MsFadD32 and adenylate analog- and phosphopantetheine-bound PA1221 protein. The N- and C-terminal domains of... the perioperative human digital twinWebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier proteins ... (for 4′-phosphopantetheine 10). The binding of dephospho-CoA was also shown to be competitive with both ATP and phosphopantetheine, whereas ... sic code for events companyWebLegend. Settings. Analysis the perioperative periodWebFeb 1, 2024 · The reaction mechanism of PPAT involves a nucleophilic attack by 4′-phosphate of phosphopantetheine on the α-phosphate of ATP in an in-line displacement … the perioperative handbookWebMay 30, 2024 · FIGURE 2.(A) Structural superposition of apo Mab PPAT in complex with feed-back inhibitor CoA (grey), PDB code 7YXZ and product dpCoA (green), PDB code 5O08, showing conformational differences in the enzyme and ligand binding mode.(B) The pantetheine moiety of CoA adopts a similar conformation to that of dpCoA. However, the … sic code for fencing contractorWebIts deduced protein was most related to mouse U26. Thus, we termed it human U26. This putative protein contains an AMP-binding domain, a Phosphopantetheine-binding … sic code for fencing companysic code for engraving