WebOct 23, 2013 · The results suggest that some type I domains covalently incorporated in multidomain contexts possess potential protein binding sites missing in the equivalent regions of their respective structural templates. ... This 1136 residue long sequence is atypical since it does not possess a recognizable phosphopantetheine binding domain … WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier …
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine …
WebJul 1, 2003 · Phosphopantetheine adenylyltransferase (PPAT) regulates the key penultimate step in the essential coenzyme A (CoA) biosynthetic pathway. PPAT catalyzes the reversible transfer of an adenylyl group from Mg2+:ATP to 4′-phosphopantetheine to form 3′-dephospho-CoA (dPCoA) and pyrophosphate. WebThe mitochondrial acyl carrier protein (human ACPM, yeast Acp1) is an essential mitochondrial protein. Through binding of nascent acyl chains on the serine (S112)-bound … sic code for energy company
4′‐Phosphopantetheine corrects CoA, iron, and dopamine …
WebAlthough holo-acyl carrier protein synthase, AcpS, a phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until the publication of the landmark paper by Lambalot et al.in 1996 that PPTases garnered wide-spread attention being classified as a distinct enzyme superfamily. WebJun 3, 2010 · Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine. ... Find proteins for P9WPA5 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WPA5 . Go to UniProtKB: P9WPA5. Entity Groups Sequence Clusters: WebProtein Phosphopantetheine-binding Status UniProtKB unreviewed (TrEMBL) Organism Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908) Amino acids 92 Protein existence Predicted Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add Add a publication Entry … sic code for family investment company