Phospho sting
Web产品说明. The Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING activation in human monocyte populations among peripheral blood mononuclear cells (PBMCs). CD45 is a pan leukocyte marker. Monocytes and dendritic cells (DCs) are ... WebMay 28, 2024 · STING activation has been shown to be a promising strategy to treat cancers, leading to the development of small-molecule agonists (9, 36). diABZI is a small-molecule, non-CDN STING agonist that is more potent than endogenous CDNs . diABZI significantly suppresses SARS-CoV-2 infection in primary and transformed human …
Phospho sting
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WebCell Signaling Technology's Phospho-STING (Ser366) (D7C3S) Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D7C3S) Rabbit mAb Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such … WebCell Signaling Technology Inc rabbit monoclonal anti human phospho sting ser366 d8k6h Rabbit Monoclonal Anti Human Phospho Sting Ser366 D8k6h, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
WebJan 29, 2015 · STING is an essential adaptor protein in the cytosolic DNA sensing pathway that also activates IRF3 . Recently, STING Ser 366 was shown to be important in IRF3 … WebThe Mouse Phospho-STING (Ser365) assay measures mouse STING when phosphorylated at Ser365. Unlike Western Blot, the assay is entirely plate-based and does not require gels, electrophoresis, or transfer. The Mouse Phospho-STING (Ser365) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor.
WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced … WebJun 7, 2024 · STING is also phosphorylated at Ser365 by ULK1, and this phosphorylation is required for the termination of the STING signalling 14. STING is an endoplasmic reticulum (ER)-localized...
WebPhospho-STING (Ser366) (D8K6H) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / …
WebInvitrogen Anti-Phospho-STING (Ser366) Polyclonal, Catalog # PA5-105674. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody … data system integration groupWebJul 7, 2024 · The Stimulator of Interferon Genes (STING) pathway initiates potent immune responses upon recognition of DNA. To initiate signaling, serine 365 (S365) in the C … data systems and services branchWebPhospho-STING/TMEM173-S366 Rabbit pAb (AP1223) Datasheet SDS. Tested applications: WB Reactivity: Human. Western blot analysis of THP-1, using Phospho-STING/TMEM173 … data system chatWebPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide … bitter panicum in beachesWebSTING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and … data system recoveryWebSTING activation in patient tumors and in platinum-treated preclinical NSCLC models was correlated with biomarkers of immunotherapy response. Results: STING activation is associated with higher levels of intrinsic DNA damage, targetable immune checkpoints, and chemokines in treatment-naive and relapsed lung adenocarcinoma. data systems chief mosWebInterestingly, we found that STING interacts with both TBK1 and IRF3, and that mutations in STING that selectively disrupt its binding to IRF3 abrogate IRF3 phosphorylation without impairing TBK1 activation. ... IRF3 also bound to phospho-TBK1 [TRAF family member-associated NFκB activator (TANK)-binding kinase] (Fig. 4 E and G), which is a ... bitter part of an orange crossword