Lamp1 tumor
Tīmeklis2024. gada 19. jūl. · By comparative proteomic analysis and differential response to neutralization of endosomal pH, we identify a few surface proteins likely specific of either exosomes (LAMP1) or ectosomes (BSG,... TīmeklisThe two glycoproteins were detected in the cytosol of tumor cells with varying intensity, LAMP-1 showing again enhanced expression. In conclusion, novel data on LAMP-1 …
Lamp1 tumor
Did you know?
TīmeklisThe gene LAMP1 (lysosomal associated membrane protein 1) encodes a membrane glycoprotein that functions as an intracellular receptor. It is found to be expressed in the cytoplasm of several types of tumor cells and may be involved in tumor invasion. Lamp1 is crucial for perforin trafficking to the lytic granules and motility of these lytic ... TīmeklisConclusion: These results show that LAMP-1 and LAMP-2 are activation markers for normal mast cells. The lack of LAMP translocation after activation of leukemic mast …
Tīmeklis2024. gada 1. aug. · LAMP proteins are involved in many different aspects of cell biology and can influence cellular processes such as phagocytosis, autophagy, lipid transport, and aging. Interestingly, for all the five members identified so far (LAMP1, LAMP2, LAMP3, CD68/Macrosialin/LAMP4, and BAD-LAMP/LAMP5), a role in cancer has … Tīmekliswe demonstrate that LAMP1 is a direct target in UBL4A-induced tumor suppression and inhibition of autophagy. HPbetaCD and HPgammaCD facilitate cholesterol …
Tīmeklis2016. gada 16. maijs · LAMP1 was directly regulated by tumor-suppressive miR-320a and contributed to cancer cell aggressiveness. The identification of novel … Tīmeklis2024. gada 22. sept. · The autophagy-related proteins AMPK, Raptor, mTOR, p62, LC3B, atg7, Rab7, LAMP1, LAMP2, and cathepsin D were detected by Immunoblotting. The antitumor effect of ARCSP was explored in vivo by establishing a transplant tumor model in nude mice. Results The results demonstrated that ARCSP induced cell …
Tīmeklis2024. gada 10. apr. · Autophagy, an important cellular stress response mechanism, is often exploited by a variety of cancer cells to sustain rapid growth under stresses such as nutrient deprivation and hypoxia. Autophagy also plays a key role in tumor resistance to chemotherapy, radiotherapy or targeted therapy. Inhibition of autophagy is …
TīmeklisLAMP1, as a marker of the lysosome has been used to assess the number of lysosomes. Downregulation of LAMP1 inhibited PCa cell proliferation, invasion, and … setup timecode traktor scratchTīmeklis2024. gada 30. marts · Lysosomal biogenesis was monitored using immunoblotting of three lysosomal membrane proteins: lysosome-associated membrane proteins 1 and … setup time hold time介紹set up time for jb weldTīmeklisThen, transplanted tumor models of A549 cells on BALB/c nude mice were established and treated with the recombinant plasmids carried by attenuated Salmonella to induce RBM5 overexpression in tumor tissues. RBM5, LC-3, LAMP1, and Beclin1 expression was determined by immunohistochemistry staining in plasmids-treated A549 xenografts. set up time clock windows 10TīmeklisThis Anti-LAMP-1 (CD107a) Antibody is validated for use in WB, IC for the detection of LAMP-1 (CD107a). Key Applications. Western Blotting. Immunocytochemistry. Application Notes. Western Blot (Snap i.d.) Analysis: 1 µg/mL from a previous lot detected LAMP-1 in 10 µg of EL4 cell lysate. Immunocytochemistry Analysis: 1:500 … set up time hold timeTīmeklis2016. gada 15. jūl. · Abstract Lysosome-associated membrane protein 1 (LAMP1) is involved in the maintenance of lysosome membrane integrity and phagolysosome formation. LAMP1 shows very limited expression at the cell surface in normal tissues while, a moderate to high expression was found in a number of solid tumors. the top madTīmeklisLAMP1 is ubiquitously expressed and highly conserved. It localizes mainly to lysosomes [ 2 ] although a small portion is detected on the cell surface. It was found that highly … the top major crash for 16 year olds in pa