Flt3 ligand peprotech

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WebNov 1, 2000 · Here we describe a flt3-ligand (FL)-dependent BM culture system that generated DCs with more diverse phenotypic characteristics. Murine BM cells cultured at high density in recombinant human FL for 9 days developed into small lymphoid-sized cells, most of which expressed CD11c, CD86, and major histocompatibility complex (MHC) … WebDescription. Mouse FLT3L was initially cloned from a murine T cell line, P7B-0.3A4; the human and mouse FLT3L proteins share 72% amino acid identity. FLT3L is synthesized as a type I membrane-bound protein, …

Flt3 Ligand - an overview ScienceDirect Topics

WebJul 31, 2013 · pDC were cultured at 0.25 × 10 6 cells/mL with TLR7 and TLR9 ligands in RPMI medium supplemented with 10% fetal calf serum, penicillin/streptomycin, l -glutamine, nonessential amino acids, and 20 ng/mL of human recombinant Flt3-ligand (PeproTech). Supernatants were collected after 40 hours and assessed for cytokine production. WebDec 16, 2015 · The transcriptional levels and the ligand-dependent autophosphorylation of FLT3 were decreased in the mutant clones. TALENs-mediated FLT3 haplo-insufficiency impaired cell proliferation and colony ... can dogs eat pitted dried plums

Imiquimod-induced CCR9 Ameliorates murine TNBS Colitis

Web产品详情规格：10mg，25mg，50mg，100mg 货期：2-3周纯度：95%以上级别：杂质对照品，医药级别用途：实验用途，科学研发，申报专用，可定制服务深圳振强生物技术有限公司(www.chem-strong.com)致力于为医药科学研究领域提供优质产品和服务。产品 WebMar 1, 2012 · Cells were cultured for 7 days with IL-3, GM-CSF, Flt3 ligand, and stem cell factor (all 10 ng/mL). DC (CD11c + Gr-1 −) and neutrophil (CD11c − Gr-1 +) potential was analyzed by flow cytometry. WebJul 1, 2024 · ATF3 is a transcriptional regulator of serine synthesis and one-carbon metabolism • ATF3 drives serine metabolism to maintain purine and pyrimidine pools Summary Metabolic reprogramming is a common feature of many human cancers, including acute myeloid leukemia (AML). fish stew recipes without tomatoes

IRF-8 extinguishes neutrophil production and promotes dendritic …

Mouse Flt-3 Ligand (FLT3L) Recombinant Protein

WebThe human and mouse Flt‑3 Ligand proteins show cross-species activity. Flt-3 Ligand is also structurally related to M-CSF and SCF. Flt-3 Ligand is widely expressed in various human and mouse tissues. It is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts (1, 8). WebAug 23, 2024 · Using multiple genetic and pharmacologic models, we show that on-target FLT3 therapy induces a cell-autonomous autophagy response that can be therapeutically exploited to significantly enhance... can dogs eat pitted fresh cherriesWebPeproTech人造血干细胞扩增用细胞因子套装(IL-3)(无动物成分)是由美国PeproTech(派普泰克)公司中国代表处代理或销售的PeproTech品牌的试剂，产品来源于美国。美国PeproTech(派普泰克)公司中国代表处是中国最权威的PeproTech人造血干细胞扩增用细胞因子套装(IL-3)(无动物成分)试剂销售服务商之一，在苏州等 ... fish stews

"WebThe flt3 ligand is a member of a small family of growth factors that stimulate the proliferation of hematopoietic cells; other members of this family include Steel factor (also known as mast cell growth factor, stem cell factor, … " - Flt3 ligand peprotech

Flt3 ligand peprotech

Cell transformation by FLT3 ITD in acute myeloid leukemia …

WebFlt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other … WebFlt-3 ligand as a DC growth factor in mice. Flt-3 ligand (Fms-like tyrosine kinase receptor 3 ligand) stimulates the proliferation of stem and progenitor cells through binding to the Flt …

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WebAccession Number: P49771 Description: Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation.FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the … WebDec 11, 2024 · While significant progress has been made in the treatment of acute myeloid leukemia (AML), not all patients can be cured. Mutated in about 1/3 of de novo AML, the FLT3 receptor tyrosine kinase is an attractive target for drug development, activating mutations of the FLT3 map to the juxtamembrane domain (internal tandem duplications, …

WebHumanKine FLT3 Ligand is expressed in human HEK 293 cells as a glycosylated monomer with an apparent molecular mass of 24-30 kDa. HumanKine FLT3 Ligand in human HEK … WebSep 18, 2024 · Cytokines should be added before use at the following concentrations: 1.5 ng/mL SCF and 1 ng/mL thrombopoietin (TPO) for flat-bottom plate culture, and 3 ng/mL SCF and 0.1 ng/mL TPO for round-bottom plate culture. See Materials and Equipment for further details. Optional Steps 12.

WebApr 6, 2024 · We had previously shown that THY1 (CD90) is a tumor suppressor in nasopharyngeal carcinoma (NPC) and that its down-regulation and loss of expression are associated with tumor metastasis, yet the mechanism leading to such effects remains unknown. In this study we show that tumor invasion could be suppressed by THY1 via … WebPeproTechflt3 ligand. Flt3 Ligand, supplied by PeproTech, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article …

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WebMouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L) ELISA Kit 供应商 Reddot Biotech 产品货号 RD-Flt3L-Mu 产品报价￥询价/96T ￥询价/48T 产品说明书点击查看购买方式银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868 产品新闻 … fish stew slow cooker recipeWebDescription: Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3 … can dogs eat pitted datesWebPeproTech fms like tyrosine kinase 3 flt3 ligand Fms Like Tyrosine Kinase 3 Flt3 Ligand, supplied by PeproTech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. fish stew tomato basedWebOct 8, 2009 · To prepare FLT3-DCs, bone marrow cells were cultured in RPMI 1640 medium supplemented with 10% FBS, 50 μM 2-mercaptoethanol, 10 mM HEPES, pH 7.4, and 100 ng ml −1 human FLT3 ligand (Peprotech) for 8 days. 293T cells were obtained from the American Type Culture Collection (ATCC) and were maintained in DMEM … fish stew recipe with potatoesWebRecombinant Murine Flt3-Ligand 250-31L-10ug from PeproTech Biocompare: The Buyer's Guide for Life Scientists. can dogs eat plain popcornWebJul 1, 2024 · FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and activation of its intrinsic tyrosine kinase activity. Activation of FLT3 leads to its autophosphorylation and … fish stew wine pairingWebPeproGMP Human Flt3-Ligand GMP300-19-50UG 50 μg GMP300-19-100UG 100 μg GMP300-19-1MG 1 mg PeproGMP Human Heregulinb-1 GMP100-03-50UG 50 μg GMP100-03-100UG 100 μg GMP100-03-1MG 1 mg ... Please contact [email protected] for our most up-to-date product list. Note: these … fish stew with potatoes and corn