Cisplatin nursing implications
WebFeb 28, 2024 · Three mechanisms define cisplatin’s direct involvement, demonstrating the chemo-resistant tumor cell phenotype: pre-target, on-target, and post-target resistance [ 20, 21, 22 ]. The first is characterized by reduced intracellular accumulation and increased cisplatin sequestration caused by GSH and other scavengers. WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel …
Cisplatin nursing implications
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WebHere are some of the nursing diagnoses that can be formulated in the use of these drugs for therapy: Acute pain related to GI, CNS, and skin effects of the drug. Disturbed body … WebREDUCED URINE OUTPUT ANOREXIA NAUSEA VOMITING (uncontrolled by antiemetics) FLUID RETENTION WEIGHT GAIN
WebTheophylline can cause nausea, vomiting, CNS stimulation, nervousness, and insomnia. [1] Nursing Considerations Across a Life Span The long term use of these drugs with childhood asthma needs to be reassessed. Although for alleviating symptoms in children they are considered a first line preventer, evidence questions the reliability of these drugs. WebCNS: Asthenia, headache, hot flushes, pain, dizziness, depression, paresthesia, malaise, insomnia, confusion, anxiety, nervousness. CV: Chest pain, hypertension, thrombophlebitis, edema. GI: Diarrhea, nausea, vomiting, constipation, abdominal pain, anorexia, dry mouth, increased liver function tests (ALT, AST, GGT).
Assessment & Drug Effects 1. Obtain baseline ECG and cardiac monitoring during induction therapy because of possible myocarditis or focal irritability. 2. Lab tests: The following tests should be done beforeinitiating every course of therapy and repeated each week during treatment period: serum uric acid, … See more A heavy metal complex with platinum as central atom surrounded by 2 chloride atoms and 2 ammonia molecules in the cis chemical position. Biochemical properties similar to those of bifunctional alkylating agents. Produces … See more Established combination therapy (cisplatin, vinblastine, bleomycin) in patient with metastatic testicular tumors and with doxorubicin for metastatic ovarian tumors following appropriate … See more Cell cycle-nonspecific, i.e., effective throughout the entire cell life cycle. Carcinogenicity has not been fully studied, but other compounds with similar action mechanisms and mutogenicity have been studied. See more History of hypersensitivity to cisplatin or other platinum-containing compounds; impaired renal function; myelosuppression; impaired hearing; history of gout and … See more WebFeb 16, 2024 · Cisplatin can affect your nervous system, increase your risk of bleeding or infection, or harm your kidneys. Call your doctor if you have a fever, mouth sores, cough, …
WebWhat are the major nursing considerations for digoxin? - IT'S POISON SO TAKE IN SMALL DOSES - CAUSE HEART TO BEAT MORE FORCEFULLY AND SLOWLY - careful patient monitoring - digoxin toxicity - hypokalemia - do not take antacids or antidiarrheals within 2 hours - physician and lab appointments - monitor pulse rate (60-100 bpm) - daily …
Webwhat is the dose-limiting toxicity for cisplatin? - kidney injury. what are the other major toxicities associated with cisplatin? - tinnitus/hearing loss. - peripheral neuropathy. - … chinese delivery near me 75243WebCisplatin dosing, indications, interactions, adverse effects, and more Drugs & Diseases cisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum... grand graphisteWebStudy this Cisplatin NCLEX mnemonic and other mnemonics with Pixorize.Cisplatin is a chemotherapy drug used to treat a wide variety of cancers. Side effects ... chinese delivery near me 23464WebNursing Implications Assessment & Drug Effects Monitor BP and heart rate continuously through period of drug administration. Lab tests: Monitor urinalysis, kidney & liver functions, and hematologic studies periodically. Monitor serial tests of vancomycin blood levels (peak and trough) in patients with borderline kidney function, in infants grand griffith investments pty ltdWebNurses play a major role in administering cisplatin and in preventing and managing the adverse effects associated with this drug. In order to maximize the quality of life of … chinese delivery near me 78229WebIf cisplatin escapes from the vein it can cause tissue damage. The nurse or doctor who gives cisplatin must be carefully trained. If you experience pain or notice redness or … grand green family hotel oberhofgrand-grandfather