WebThe target genes of the c-MYC protein participate in different cellular functions, including cell cycle, survival, protein synthesis, cell adhesion, and micro-RNA expression. c-Myc is also one of the four factors used in reprogramming somatic cells to induce pluripotent stem (iPS) cells and is implicated in maintaining cancer stem-like cells … WebOct 18, 2024 · A comprehensive review about Myc tag antibody, and a summary of myc antibody applications from over 200 publications. The c-Myc protein is an oncogenic transcription factor, encoded by the c-Myc gene on human chromosome 8q24. The c-Myc protein is implicated in several physiological processes including proliferation, …
Anti-Myc Tag Antibody, clone 4A6 - Sigma-Aldrich
WebThe proliferation of P19 cells was significantly enhanced by SB216763, as well as c-myc overexpression. C-myc downregulation inhibited P19 cell proliferation caused by activation of Wnt/β-catenin signaling and induced P19 cell differentiation. In conclusion, activation of the Wnt/β-catenin pathway could promote the proliferation and inhibit ... WebThe transcription factor C-MYC by C-MYC dimerizes with MAX and binds to the target DNA sequence or E-BOX (sequence 5'-CANNTG-3') to regulate transcriptional proliferation of genes involved in cell growth and apoptosis. lowes outdoor gas fire pit
c-Myc Antibody Cell Signaling Technology
WebEmerging roles of C-myc in cancer stem cell-related signaling and resistance to cancer chemotherapy: a potential therapeutic target against colorectal cancer. ... and 0.01% NaN 3 for 30 min, and then stained overnight in 4°C with Myc antibody (Abcam cat. 32072) in blocking buffer. After PBS wash, secondary antibody (Alexa Fluor, ThermoFisher ... WebMar 21, 2024 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit . Among its related pathways are Prolactin Signaling and Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants . WebThe c-Myc (D84C12) Rabbit mAb Antibody from Cell Signaling Technology is a Rabbit Monoclonal antibody to MYC. This antibody recognizes Human, Mouse, and Rat antigen. The c-Myc (D84C12) Rabbit mAb Antibody has been validated for the following applications: Immunocytochemistry, Immunofluorescence, and Western Blot. lowes outdoor handrail